Evaluation of the effect of interaction immobility stress and forced running on a treadmill on learning and spatial memory and serum corticosterone levels in male Wistar rats

The aim of this study was to compare the effect of forced exercise with treadmill, immobility stress and imultaneous application of stress + treadmill exercise on learning and spatial memory and serum corticosterone levels.

Rats in four groups (10 rats in each group) were randomly exposed to treadmill exercise, immobilization stress, both together or without intervention for four weeks. Assessment of learning and spatial memory Performed using the Morris water maze device. After the last session, direct blood samples were taken from the left ventricle to measure cortisol.

The results showed that in the treadmill training group and also in the stress group, the average distance traveled to reach the platform was higher than the control group (p