Prognosis of Acute Hypotension Episodes Using Physiological and Chaotic Features

Acute hypotension episodes (AHEs) are one of the hemodynamic instabilities with high mortality rate that is frequent among many groups of patients. Prognosis of acute hypotension episodes can help clinicians to diagnose the cause of this physiological disorder and select proper treatment based on this diagnosis. In this study two groups of features, physiological and chaotic features, were extracted from the physiological time series to be applied for prediction of AHEs in the future 1 hour time interval. The best set of the features from the extracted features were selected using Genetic Algorithm (GA) and were classified by SVM. The prediction accuracy for physiological features was 87.5% and for chaotic features was 85%. In order to improve prediction accuracy, physiological and chaotic features were employed simultaneously in feature selection and the best combination of these features was selected by GA and classified by SVM. The best prognosis accuracy, which was achieved in this study by classification of the selected features, was 95% that was better than other previously studies on the same database.