Evaluation of the Pregnancy Rate of Freezing Embryo Transfer in the Presence or Absence of Gnrh Agonist

Recently, the use of assisted reproductive technologies (ART) is increasing day by day. one of the critical steps in art is the frozen embryo transfer, in which the endometrium thickness has great importance in outcome. In this case, the frozen embryo will be transferred during the next cycle. There are several ways to prepare an endometrium for transmitting embryos, however, choosing the best method is still debated.  The present study aimed to evaluate the pregnancy rate of frozen embryo transfer in the presence or absence of GnRH agonists.

 A retrospective analysis was conducted of 146 consecutive patients attending Qomchr('39')s infertility treatment center since 2015 to 2017 who were candidates for the transfer cycle of the frozen-thawed embryo were randomly assigned to receive either protocol with or without GnRH agonist. Clinical features, implantation rate, pregnancy rate (chemical and clinical), and abortion rate were assessed.

There was no significant difference in baseline and clinical characteristics, implantation rate, pregnancy rate (chemical and clinical), and abortion rate between two groups of endometrial preparations with or without GnRH agonist (P <0.05).

In this study, pregnancy outcome was similar in each group and this method is recommended as an endometrial preparation without GnRH agonist.