Comparison of Fatty Liver Disease in Men with and without Androgenetic Alopecia

Fatty liver disease is the most common chronic liver disorder, which is introduced as part of the metabolic syndrome. On the other hand, androgenetic alopecia in men, which is the most common cause of hair loss, can also be associated with cardiovascular disease and metabolic disorders. Due to the common risk factors for fatty liver and androgenetic alopecia, this study was performed to compare the frequency of fatty liver in men with and without androgenetic alopecia.

In this cross-sectional study, 140 men aged 25 to 55 years (70 men in two groups of men with and without androgenetic alopecia), who referred to the dermatology clinic for cosmetic reasons, volunteered to participate in the study. Age, body mass index, abdominal circumference, smoking history, extent of hair loss and liver ultrasound results were evaluated and compared in the two groups.

The mean age of participants was 35.84±7.90 years. There was no statistically significant difference between the two groups in terms of age, smoking, and abdominal circumference. 54 men with androgenetic alopecia (77.1%) had fatty liver, while 41 people in the group without androgenetic alopecia (58.6%) had fatty liver, which showed a significant difference (p=0.019). Grade one and three fatty liver was significantly higher in patients with androgenetic alopecia compared to the group without androgenetic alopecia (p=0.011). There was no statistically significant relationship between the grade of fatty liver and the extent of androgenetic alopecia (p=0.059), but the extent of hair loss in obese individuals was significantly higher (p<0.001).

According to the findings of this study, fatty liver disease has a significant frequency in men with androgenetic alopecia.