Evaluation of serum fat changes in type 2 diabetic patients treated with premixed insulin during the holy month of Ramadan

Diabetes mellitus is the most common metabolic disorder which according to some research, is the most common endocrine disease and a threat to global health. However, many people with diabetes insist on fasting.

This study was conducted with a cohort of 94 insulin-treated type 2 diabetic patients in the low to moderate risk group for 3 months. These patients were divided into two groups, including43 fasting patients and 51 non-fasting patients. Finally, data were analyzed through SPSS software version 22. In order to describe the variables, two types of statistical procedures, namely independent and paired t-test or their non-parametric equivalents were used.

It was indicated that there was a statistically significant difference in Weight, triglyceride (p<0.05), high-density lipoprotein (p<0.01), low-density lipoprotein (p<0.05) and concentrated lipoprotein (p<0.05) between the two groups. Separation study of the studied groups showed that weight gain, triglycerides, LDL, VLDL and total cholesterol in the control group were the cause of the above changes and only LDL significantly decreased and HDL significantly increased (p≤0.05).

Fasting with a regular diet and an exercise program during Ramadan, even in diabetic patients treated with premixed insulin, has a beneficial effect on lipid and lipoprotein factors.