Multıparametric Prostate Magnetic Resonance Imaging Before Radical Prostatectomy: Can it Predict Histopathology?

We aimed to investigate the histopathological correlation of the suspected prostate malignancy detected in multiparametric prostate magnetic resonance imaging (mpMRI).

The data of 93 patients who underwent radical prostatectomy and had preoperative mp-MRI were examined. Age and pre-operative Prostate-Specific Antigen values were retrospectively collected from patient files. The pathology specimens were examined again and post-operative ISUP grade group, other patho-logical findings (seminal vesicle invasion, lymph node involvement, and extraprostatic extension), pre-operative mpMRI were re-examined and PIRADS score, extracapsular extension, seminal vesicle invasion, neurovascular bundle invasion, lymph node involvement, and ADC values were recorded.

151 (92,07%) of 164 lesions detected in mpMRI were histopathologically correlated. 80% of patients with seminal vesicle invasion (P < 0.001), 28.8% of patients with extracapsular extension (P < 0.052) and 42.9% of patients with lymph node involvement (P = .001) in mpMRI were histopathologically correlated. A significant relationship was found between PIRADS scores and ISUP grade groups (P < 0.001). There was a negative corre-lation between ADC values and ISUP grade groups (P < 0.001).

Our study showed that the lesions detected by mpMRI showed a high histopathological correlation