The Effect of Curcumin on HDL Cholesterol Uptake Capacity in Obese Individuals: A Pilot Study

Author(s):

Maryam Saberi-Karimian , Mina Nosrati , Arezoo Orooji , Tooba Kazemi , Ali Javandoost , Akram Mohammadi , Gordon A. Ferns , Malihe Aghasizadeh * , Majid Ghayour-Mobarhan

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Introduction

Obesity is a common risk factor associated with cardiovascular disease (CVD) risk. Curcumin has been reported to exert beneficial effects on lipid metabolism, including HDL functionality. We have examined the effects of curcumin on HDL cholesterol uptake capacity in subjects with obesity.

Materials and Methods

30 obese individuals received curcumin and placebo 1 g per day for a period of 30 days. The subjects were crossed over to the alternative regimen after a 2-week washout period. A modified cholesterol uptake capacity (CUC) assay was used to determine serum HDL functionality.

Results

The study groups had similar base line characteristics. We did not find significant effects (p>0.05) of curcumin on serum HDL CUC levels.

Conclusion

Curcumin administration at a dose of 1 g per day for 30 days did not affect HDL CUC in subjects with obesity.

Keywords:

Curcuma longa , Curcumin , Cholesterol Uptake Capacity , metabolic syndrome

Language:
English
Published:
Journal of Cardio -Thoracic Medicine, Volume:9 Issue: 3, Summer 2021
Pages:
833 to 838
https://magiran.com/p2326260  
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