Determining the effect of changes in respiratory rate in conclusion of weaning from mechanical ventilation in intensive care unit

The aim of this study was to determine the effect of changes in respiration rate on the outcome of weaning from mechanical ventilation in patients admitted to the intensive care unit of Golestan Hospital in Ahvaz in 2020.

The present study was a cross-sectional and analytical study. The statistical population of the study was all patients under mechanical ventilation admitted to the intensive care unit of Golestan Hospital in Ahvaz from April to June 2020. The sample size in the present study was 135 people. SPSS 24.0 software was used for data analysis. The significance level for all tests was 0.05.

The highest frequency of the need for mechanical ventilation in the studied patients was postoperative, acute brain injury and respiratory distress. Based on the findings of the present study, a total of 52.6% of patients under mechanical ventilation had successful separation. The cut-off rate of respiration for successful separation from mechanical ventilation was RR > 20. According to the findings, for approximately 67% of patients with RR <20, the result of separation from mechanical ventilation was successful, and for 60% of patients with RR> 20, the result of separation was unsuccessful. Sensitivity and specificity were obtained by determining the cut-off RR > 20 equal to 70% and 60%. In other words, 70% of patients with unsuccessful separation resulted in RR> 20 and 60% of patients with successful outcome had RR <20.

Based on the results of the present study, the respiratory rate had a significant relationship with the result of weaning from mechanical ventilation. Patients with high respiratory rate have deliberately had the result of weaning from poor mechanical ventilation. Also, the sensitivity in the present study was obtained with a cut of RR> 20 times 70%. 60 percent of patients who had more than 20 breaths had a successful separation outcome.