Harvesting Tissue from Teeth-related Structures as a Source of Stem Cells

The tooth bud comprises of aggregation of cells demarcated as enamel organ, dental papilla, and dental follicle. They produce different parts of tooth and its supporting structures. More attention is paid to the teeth and its related structures as sources of mesenchymal stem cells (MSCs). Using dental sources has many advantages, such as easy access and less ethical consideration. MSCs from these tissues, besides In vitro achievements, showed effective results in clinical applications, especially in oral and maxillofacial regeneration.  The case selection and how to harvest the tissue from teeth structures are rarely described. In this concise review, the criteria of subject and teeth selection as a source of MSC isolation were assessed and how to harvest the considered tissue was also discussed.