Electroanalytical Techniques used in Determination of Tamoxifen

Tamoxifen (TAM) is a selective estrogen receptor modulator used in the treatment of breast cancer, women’s infertility and some other endocrine diseases. TAM is a generic medication that is prescribed relatively a lot. Due to the impact of this medication and its side effects, screening TAM level in biological samples and in pharmaceutical formulations are of great importance. Various analytical techniques are developed for the detection or monitoring TAM levels in different matrices. Since TAM chemical structure is able to undergo electrochemical oxidation, electrochemical techniques due to their remarkable features are also considered as analytical methods. Here, electroanalytical measurements of TAM will be reviewed.