Survey of Platelet-Riched Plasma Injection with and without Calcium Gluconate in Treatment of Patients with Knee Osteoarthritis

The most common cause of knee pain is knee osteoarthritis, many surgical and non-surgical treatments have been proposed but the preferred treatment remains unknown. One of the non-surgical treatments was PRP (plasma reach platate) injection in these patients. Various studies have shown the improvement of the effect of PRP injection with substances such as calcium gluconate, so the aim of this study was to evaluate the effectof PRP with and without calcium gluconate on the clinical results of intra-articular injection of this substance in patients with knee osteoarthritis.

This was a cohort study in which patients were divided into two groups: PRP injection and PRP injection with calcium gluconate. The results of the study were evaluated by KOOS questionnaire and pain by VAS. A significance level of 0.05 was considered.

Generally, during the study, the pain level in patients after receiving both treatments significantly decreased during the six-month period, while the pain in the case group significantly decreased. (P Value <0.05).

From the results of this study, it can be concluded that simultaneous injection of PRP and calcium gluconate can further improve the results of injection.