Evaluation and comparison of changes in some metabolic and oxidative parameters before and after calving in Holstein dairy cows

In the recent years, due to the role of oxidative stress in the pathogenesis of various diseases, oxidative stress markers have become a useful tool in the prevention and treatment of various diseases. Regarding the importance of dairy cattle transition period and little research on the state of oxidative stress during the transition period, the aim of this study was to investigate the status of oxidative stress during the transition period using Malondialdehyde (MDA), glutathione (GSH) and total antioxidant capacity (GSH) two weeks before and after parturition in Holstein dairy cows in Shahrekord dairy farms.

42 dairy were selected from one of the industrial dairy farms in Shahrekord. Blood samples were taken two times (two weeks before and after pregnancy) and was transferred to the laboratory for measurement of Malondialdehyde, glutathione and total antioxidant capacity. T-test was used to compare the mean of each of these parameters before and after pregnancy.

The mean serum Malondialdehyde level after parturition in comparison to before parturition increased, although it was not statistically significant (P>0/05). The mean glutathione and total antioxidant capacity of the blood after delivery in comparison with the prepartum were significantly decreased (P<0/05). Also, the levels of superoxide dismutase, catalase and glutathione peroxidase enzymes decreased significantly after delivery compared to before delivery (P <0.05).

According to the results of this study, it can be concluded that dairy cows are exposed to oxidative stress during the transition period, although they do not show clinical symptoms. As a result, it is important to pay attention to the use of antioxidants during the transition period.
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