Immunity Markers in SARS-CoV-2 with Lessons Learned from H1N1 Flu Pandemic

A novel outbreak with global implications, COVID-19 can be compared with the 1918 Spanish flu in many aspects. Thus, preventive and therapeutic strategies that once proved to be effective in the containment of the old pandemic, such as self-isolation and convalescent plasma therapy, respectively, might once again come to our aid and prevent further outbreaks of the disease in the years to come. In our opinion, the COVID-19 pandemic can be harnessed in a way similar to the Spanish flu, provided that the preventive and therapeutic strategies are properly executed.