The Risk Factors in Serum of Peripheral Neuropathy Diabetic and Type 2 Diabetes Patients

The study's purpose was to evaluate the serious risk factor for the neuropathy disease in patients with diabetes

This research was done on 120 subjects classified into 40 with DPN T2DM and 40 with T2DM and 40 healthy considered as a control. As the conditions of the Iraqi Ministry of Health to evaluate the thesis clinically, that the number of samples examined should be at least 120 samples. The collection period was from 1 October 2021 to 1 December 2021. All patients and control groups were collected from medical City Al-Imamian, Al-Kadhmiyain-Baghdad-Iraq. Regression analysis was used to investigate potential risky factorize lead for the DPN in T2DM patients.

The spread of DPN in Type 2 diabetic patients was 50% of the multiple logistic transformations revealed in diabetic peripheral neuropathy. The mean value of Duration was significant (p<0.05) for DPN compared with T2DM. The mean value of fasting glucose, HbA1c, and hypertension, for DPN participants, were significantly higher than in T2DM and control groups (p=0.0001). The analysis of variance for vitamin B12 and vitamin D was significant (p=0.0001) for DPN it was lower than for T2DM and control. The mean value of lipid profile was non-significant (p>0.05) between the three groups.

Diabetic peripheral neuropathy had a high risk of a decrease in their vitamin B12 and vitamin D levels. On another hand, patients with T2DM should follow up on their vitamin levels periodically.