Preparation of Nano Silver/Hydroxyapatite/ β-Tricalcium Phosphate Coating on Titanium Surface by Sol-gel Method

Bioactivity and antibacterial properties have been recognized as important factors which can result in the success of titanium- based replacements in the orthopedic surgeries. In the present study, silver nanoparticles (nAg) and HP particles (containing the same ratio of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP)) were coated on titanium substrate through using sol-gel method to induce both bioactivity and antibacterial properties. The prepared composite coating then was characterized via scanning electron microscopy (SEM ) equipped with X-ray diffraction (EDX), bioactivity assessment, anti-bacterial evaluation, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (M TT) test. The obtained results showed that HP/nAg coating on titanium substrate enhanced bioactivity, anti-bacterial performance, and cell viability comparable with pure titanium. The overall results indicated that the coated substrate containing HP (β-TCP/HA = 50:50) with 2% nA g on Ti plates can be a reliable candidate for further studies.