Effect of barbiturate coma on prognosis of head injury patient by Glassco coma scale<8

Head trauma is one of the main causes of disabilities and death, especially below the age of 24 years. The aim of this study was to find the effect of barbiturate coma on prognosis of head injury patient by Glassco coma scale<8. This quasi-experimental clinical trial was performed on 34 patients with a GCS<8 in intensive care unit of Shahrekord Ayatollah Kashani hospital. These patients received 2mg/Kg/h intravenous infusion of thiopental for 48 hours with mechanical ventilation. Patients evaluated with or without operation by Glassco outcome scale (GOS). Then results of this study was compared whit other studies by relative risk method. Undesirable outcome relative risk of nonoperated patients was 0.69 and of operated patient was 0.59 that confirmed the desirable effect of thiopental infusion on head injured patients’ outcome.