Effect of Swimming Training in Addiction Withdrawal Period on Thyroid Hormones in Addicted Rats

Nowadays, drug consumption is increasing in the world. Physiological changes in the body is one of the most important consequences of drug use, the most important of these changes can be hormonal changes the bodies. Therefore, the aim of this study was to investigate the effect of swimming training on thyroid hormones in addicted rats during withdrawal.

Rats were randomly divided into seven groups: (1) eight week swimming, (2) eight week methadone, (3) eight week swimming with methadone, (4) four week methadone and four week lack of methadone, (5) four week Methadone with swimming, (6) methadone, swim and swim without methadone and (7) control. Swimming training include three days a week and each section was 30 minute. Group’s methadone use two mg per kg of body weight were injected methadone daily for eight weeks. Blood samples were taken 24 hours after the last training session. For analyze the data, we used of Kolmogorov-Smirnov test and ANOVA (α = 0.05).

The results showed that eight week swimming training, eight week methadone, eight week swimming training with methadone, and also four week swimming training in during methadone withdrawal has no significant effect on thyroxin (P=0.29),Triiodothyronine(P=0.06), thyroid stimulating hormone(P=0.24) in rat.

Eight weeks of swimming, methadone, swimming with methadone and methadone withdrawal period of four weeks of swimming training in rats has no significant effect on thyroid hormones.