Comparison of the Outcome of Ventricular Septal Defect Closure Using GORE-TEX and Autologous Pericardial Patches

Despite the recent experiences and technical advances in the repair of congenital ventricular septal defects (VSDs), there is still the possibility of postoperative complications and even death among patients undergoing treatment. This study aimed to determine and compare the short-term complications of congenital anomaly (VSDs) repair using the pericardial patch and GORE-TEX patch.
 

This cohort study evaluated 100 patients undergoing VSD repair surgery in 2 repair groups of the pericardial patch (50 patients) and the GORE-TEX patch (50 patients) in Rajaie Cardiovascular Medical and Research Center between 2019 and 2020. All the patients’ information was recorded in a checklist and analyzed using the SPSS software via the Mann–Whitney and χ2 tests.
 

There was a significant difference in the duration of aortic clamping between the pericardial patch and GORE-TEX patch groups (P=0.03). The rate of complications in the GORE-TEX patch group was significantly higher than that in the pericardial patch group (34% vs 14%; P=0.01). The cost of treatment was significantly higher in the GORE-TEX patch group than in the pericardial patch group (P=0.0001).
 

The lengths of surgery, cardiopulmonary bypass, and aortic clamping, as well as short-term complications and treatment costs, were lower in the pericardial patch group than in the GORE-TEX patch group. (Iranian Heart Journal 2022; 23(4): 13-19)