~
Comparison of Biocompatibility of foreign MTA (Proroot) and Iranian MTA (Root) in Rat

Mineral trioxide aggregare (MTA) is one of the new materials that was introduced for apicectomy at first but today is used for many purposes in endodontics. This study is done due to the importance of economical points in dental materials and decreasing the dental fees and to use new products. The aim of this study was to compare tissue reaction of foreign MTA (proroot)and Iranian MTA(Root) by subcutaneous implanted tube in rat. Methods & Materials: Fifty four rats were divided into four groups of experiments (40 rat) and 2 groups of control (14 rat). In experimental groups two isolated regions were incised to implant two polyethylene tubes filled with Root and ProRoot, and in control groups two empty tubes were implanted. Animals were sacrificed after 7 and 30 days. After histopathologic preparation, H&E staining, samples were evaluated for the thickness of capsule, intensity, type and extention of inflammation and necrosis. The results were analysed by chi-square. There was no statistical difference in the tissue reaction between Root and pro Root. Root is a biocompatible material as ProRoot.