Evaluation of antibacterial activity of aqueous and ethanol extracts of Rumex alveollatus against Klebsiella pneumoniae

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Introduction

Antimicrobial resistance in Klebsiella pneumoniae has been on the increase over the years Therefore, numerous endeavors have been carried out so as to discover another active plant combination as a suitable substitute for antibiotics. This is a Experiment of the activities of antibacteria from the extract from Rumexa alveoli against ebsiella pneumonia.

Materials & Methods

This study was performed on the standard strain of Klebsiella pneumonia and several clinical strains. The aqueous and ethanol extracts of Rumex alveollatus; formulated by the Soxhlet apparatus. The activities of the antibacterial of the extracts were analyzed with the use of the disk-diffusion method. Furthermore, the minimal-inhibitory-concentration (MIC) and the MBC were examined by the micro dilution method. The database collected by SPSS recent software was evaluated.

Findings

Inhibitory zone of ethanol (500 mg/ml) on standard and clinical strains of Klebsiella pneumoniae were 18, 17, 17,15,16, and 16 mm, respectively, and also aqueous extract did not have an antimicrobial effect. MIC and MBC results for ethanol extracts were 125 and 250 mg/ml, respectively.

Conclusion

The antibacterial activities of the Rumex alveollatus ethanol and aqueous extract tested against bacteria was good . Thus, the findingss of this research can be a beneficial report concerning their active role in infection control.

Language:
English
Published:
International Journal of Advanced Biological and Biomedical Research, Volume:10 Issue: 4, Autumn 2022
Pages:
262 to 270
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