The effect of eight weeks of combined training (aerobic-TRX) and cinnamon supplementation on the serum levels of apelin and IL-6 in inactive overweight women

Today, experts believe that diet and drugs alone are not enough to treat and control sugar and blood fat metabolism of patients, but physical and sports activities should also be added to the daily schedule. Therefore, the aim of this study was to investigate the effects of a combined training course (aerobic-TRX) and cinnamon supplementation on the serum levels of apelin and IL-6 in inactive overweight women.

In this semi-experimental study with preand post-test design; 40 overweight women were randomly assigned into the four groups such as: combined exercise (n=10), combined exercise-cinnamon supplement (n=10), cinnamon supplement (n=10 people) and control (n=10). Aerobic exercise was performed with 50-75% of the maximum heart rate and TRX exercise in the range of 12 to 17 pressure perception on the Borg scale. Blood was taken 24 hours before the start of the training period and 48 hours after the end of the last session to measure apelin and interleukin-6.Then, by using covariance analysis test, between-group changes were used and paired t-test was used for intra-group comparison. Data analysis was done by SPSS version 25 software at a significance level of P<0.05.

The results between groups show a significant difference in the serum concentration of IL-6 and apelin (P=0.001). The results of the paired t-test show a significant decrease in LI-6 and Aplin values for all three groups (P<0.05).Discussion and

The reduction of inflammation caused by sports activity is one of the effective factors in reducing the level of apelin in the present study. According to the results of the present research and since combined exercise (aerobic-TRX) has a beneficial effect on apelin and interleukin-6. Cinnamon supplementation effectively reduces adipose tissue significantly, but does not affect muscle metabolism in the same way as exercise. However, both interventions may be used together as a powerful weight loss technique.