The transition to personalized medicine is necessary, but which pathway?

The emergence of technological innovations and digital medicine is making fundamental changes in the healthcare sector towards personalized medicine. Therefore, in the near future, we will have to pass from population-based medicine to personalized medicine. The purpose of this study is to identify the appropriate framework for the transition to personalized medicine.

The study method was a systematic literature review with a content meta-analysis approach. The statistical population of the research was personalized medicine articles that have been conducted during the last 12 years (2010-2022). After several screening stages of the papers, finally 7 articles have entered the meta-analysis process as samples (articles related to policy making or transition to PM).

Findings show the most of the studies in the field of PM were specialized and clinical, and only a few studies have briefly addressed the management and policy issues of PM, and the transition and transition pathways regarding PM have not been studied much.

Adapting from the proposed PM model and technological transition pathways, the framework for the transition to personalized medicine includes the transformation pathway from conventional medicine to stratified medicine and then technological substitution pathway from stratified medicine to personalized medicine. In order to appropriate policy making in this framework, we need appropriate policy tools of science, technology and innovation.