Evaluation of Corneal Aberrometry Parameters Before and After Cross-Linking in Patients with Keratoconus

In the last decade, cross-linking (CXL) has been widely used for treating people with progressive keratoconus. The present study aimed to compare corneal aberrometry parameters before and after CXL in patients with keratoconus.

In this cross-sectional study, 67 patients with keratoconus referred to Farshchian Sina Medical Education Center, Hamadan, Iran, who underwent CXL surgery at Mahdia Surgery Center, were selected. The results of refractometry and aberrometry before the surgery and six months after the CXL, were examined and compared. Data were extracted from patients’ medical records and analyzed in SPSS software (version 26). A P-valuec less than 0.05 was considered statistically significant.

The mean age of patients was 22.28 ± 5.03 years, and 65.7% were male. Mean aberrometry parameters before and six months after the treatment for K1: 44.33 and 44.04 (P=0.003), K2: 48.01 and 47.91 (P<0.001), Km: 46.27, and 45.86 (P<0.001), Kmax: 51.72 and 51.34 (P<0.001), astigmatism: 3.59 and 3.93 (P<0.001), Thanet Local: 472.76 and 462.37 (P<0.001) and CDVA: 6.41 and 8.25 (P<0.001). No significant difference was oberved between CCT, Rms Total, Rms LDA, Coma, and sphere parameters before and after the CXl.

Cross-linking is an effective method for treating keratoconus in adults, leading to the correction of most corneal aberrometry parameters, including K1, K2, Km, Kmax, astigmatism, thinnest location, and CDVA within six months.