Investigating the effect of nanoparticles with antioxidant properties on free radicals

The purpose of this study is to investigate the effect of nanoparticles with antioxidant properties on free radicals. In order to achieve the goal of the research, the content and results of valid research articles related to the subject of the current research have been analyzed and reviewed. Examining and analyzing the results of studies that have dealt with the effect of nanoparticles with antioxidant properties on free radicals, showed that nanoparticles have recently received much attention due to their many applications and unique properties. Oxidative stress is the cause of many diseases in humans. Oxidative stress is a phenomenon in which the balance between antioxidant defense and oxidants in the cell is disrupted. Antioxidants prevent damage caused by oxidants. Although antioxidants have been known for a long time, research on improved natural or synthetic antioxidants is still a topic of interest due to their important practical applications. Antioxidants may suffer from low stability under oxygen and in biological systems can be degraded before reaching their target sites; Or they can have adverse health effects that limit their use. Sometimes, it is desirable to remove the antioxidants from the homogenous system to which they have been added, after they have taken effect. In this context, nanotechnology has opened new opportunities to exploit the unique and innovative properties of nanomaterials, possibly in combination with some common natural or synthetic compounds, with the aim of achieving pioneering "nano-antioxidants" with enhanced properties. Some nanomaterials, including organic metal oxides (e.g., melanin, lignin) (i.e., cerium oxide) or metal nanoparticles (e.g., gold), exhibit intrinsic redox activity, often by scavenging radicals and/or It is associated with superoxide dismutase-like and catalase. Inorganic nanoparticles have been successfully evaluated in terms of antioxidant properties. Recently, nano antioxidants have shown the ability to reduce oxidative stress with greater sensitivity, cellular antioxidant activity and minimal cytotoxic effects and targeted delivery.