Electrochemical Reduction of 2-Substituted Quinoxalines in Aprotic Medium and in Conditions of Protonation
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
The present work is devoted to the electrochemical reduction study of presumably biologically active 2-substituted quinoxaline derivatives. In this work, two new quinoxaline derivatives are presented. The electrochemical behavior of this compound in an aprotic medium and while its protonating was investigated via a voltammetric method. Using computational methods, the localization of the reduction centres depending on the compound’s structure was determined. The EPR spectra data obtained by electrochemical generation reduction product proved that the studied quinoxaline’s electroconversion occurs with radical anion formation. The linear correlation between the reduction potential of studied compounds and energy of their affinity to the electron was found (R2 = 0.933). This confirms the single reduction mechanism of radical nature for the entire series of studied 2-substituted quinoxaline derivatives. Based on that, the electron-accepting ability of these compounds was compared in order to evaluate their possible bioactivity and to select the most perspective ones among them for further research.
Keywords:
Language:
English
Published:
Analytical & Bioanalytical Electrochemistry, Volume:15 Issue: 3, Mar 2023
Pages:
184 to 197
https://magiran.com/p2571669
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!