Comparison of ketamine and dexmedetomidine in maintaining hemodynamic stability in laparoscopic cholecystectomy surgery with general anesthesia

One of the basic characteristics of a successful anesthesia is reversible loss of consciousness with immobility, lack of awareness, not responding to painful stimulation and not remembering surgical interventions. The present study was conducted with the aim of comparing ketamine and dexmedetomidine in maintaining hemodynamic stability in laparoscopic cerebrocystectomy surgery with general anesthesia This study was a clinical trial. 90 patients aged 18 to 44 (in two groups of 30) were evaluated with ASA І, П during general anesthesia. Inclusion criteria included ASA class one or two and consent to participate in the study. Patients were randomly divided into three groups: 1) Control and 2) Intervention with Ketamine, Intervention and 3) Intervention with Dexmedetomidine. Patients' vital signs evaluated. The findings of the research showed that between the three groups of ketamine, dexmedetomidine and control in the times before induction, after induction, 5 minutes after, 15 minutes after, 30 minutes after, 60 minutes after, in recovery and outside of recovery, in terms of There was a significant difference in mean systolic and diastolic blood pressure and mean arterial blood pressure (P<0.05), but there was no significant difference in heart rate between the three groups at these times (P<0.05). The average O2SAT in the ketamine group was lower than the dexmedetomidine and control groups (P<0.05). Based on the results of the present study, the use of dexmedetomidine in laparoscopic cholecystectomy surgery compared to ketamine causes hemodynamic stability than ketamine.