Medical and Pharmacological Evaluation of Scar Formation in Plastic Surgery

Scar management is a critical challenging object in plastic surgery that influences life quality and can induce depression and functional disturbances. Hypertrophic scars and keloids after surgery, especially in cosmetic surgeries, can cause inappropriate appearance and excess costs to decrease the scar. Moreover, spiritual disturbance and psychological problems can occur, which lead to objections against physicians. Multi-disciplinary treatments like Butax injection have been suggested. This study is a case-control type. The cases are 20 patients attending Mehr Surgical Center and Rasoul-e- Akram hospital in Tehran diagnosis of hypertrophic scars or keloids after surgical mastopexy from February 2018 to February 2019. Four characteristics like width, height, color, and pliability were studied according to surgery scar. Also, the patient’s age, smoking, pleasure, and previous history of hypertrophic scars and keloids are Surveyed. In each of the patients, Butax is injected in right breast scar without any injection in the contralateral side as a control group and all patients studied for 18 months. At the end, data was analyzed with the SPSS 22 software. This study achieved meaningful differences between with and without Butax injected groups. According to Vancouver scale, the width, height, color, and pliability achieved higher scores meaningfully. In addition, the pleasure of patients in injected groups has achieved a higher score. There was a meaningful correlation between smoking and pleasure score in these patients, but we did not find a meaningful relationship with age.