Gingival bullae -A rare visible case report

 Blistering disorders are acute or chronic autoimmune diseases affecting the skin and the mucous membranes. In mouth or any non-specific lesions like lichen planus, chronic herpesvirus infection, etc., differential diagnosis needs confirmation by biopsies, direct- and indirect- immunofluorescence. This case study is about Gingival Bullae as a rare sign of Mucous Membrane Pemphigoid (MMP), that is a blistering disease.

A 55-year-old woman without any past medical or family history was referred to the Oral Medicine Department of Semnan University of Medical Sciences by an internist with complaints of oral bullae and burning sensation. Intraoral examinations showed gingival erythema and bullae. The histopathology result after biopsy reported that this Gingival Bullae is related to MMP. An oral corticosteroid was administered and no recurrence was observed at 2-year follow-up.

Dentists could be the first healthcare professionals to identify this rare mucocutaneous lesion, ensuring early diagnosis and treatment. This, in turn, determines the prognosis and course of the disease. Multidisciplinary cooperation is recommended.