Recent Progress on 1,2-Hydroxyfluorination of Alkenes
The direct fluorinative difunctionalization of alkenes is one of the most convenient platforms to the structurally complex organofluorine compounds from bulk chemicals. Accordingly, tremendous efforts to explore synthetic methodologies in this research area have been documented. In this family of reactions, the direct hydroxyfluorination of simple alkenes has emerged as a sustainable and powerful synthetic strategy for the efficient construction of vicinal fluorohydrins, which are found widespread applications in the fields of human life. The purpose of this review is to provide an overview of the available evidence on the synthesis of vicinal fluorohydrins through the direct hydroxyfluorination of corresponding alkenes. Literature has been surveyed from 1999 to the end of October 2023.
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.