Adverse Drug Reactions of Multiple Sclerosis Disease-modifying Drugs

High frequency of adverse drug reactions (ADRs) challenges multiple sclerosis (MS) treatment. This study aims to assess the nature and frequency of ADRs induced by MS medications in an observational cross-sectional study. 

ADRs of all outpatients who had seen a neurologist and had received at least one disease-modifying therapy (DMT) for MS during the last three months were investigated.

A total of 484 ADRs were detected in these patients. The preventability rate was 5.9%, and 0.61% of reactions were serious.

The high frequency of adverse drug reactions in this study shows a strong need for strategy planning to increase patients’ adherence to treatment.