The effect of eight weeks of ketogenic diet and resistance training on insulin resistance index and lipid profile in women with polycystic ovary syndrome

     PCOS is a common endocrine disorder in women of reproductive age. The present study aimed to investigate the effect of 8 weeks of resistance training and a ketogenic diet on insulin resistance and lipid profile in overweight and obese women with PCOS.

This study involved 60 women (15–40 years) with a BMI of 25-39.9 and a fat percentage of 29-38% being randomly divided into four groups. Control (n=15), diet (n=15), resistance training (n=15), and exercise+diet (n=15). The exercise group and the exercise group + diet both participated in the exercise program for 8 weeks, with the diet group only adhering to an adjusted diet. Blood was drawn from subjects 48 hours before the training period began and after it concluded.

The findings indicated that, after 8 weeks, there was a significant disparity observed in the body composition variables, lipid profile, and insulin resistance index (p 0.05). Upon examining the post-test results compared with the pre-test results in the control group, it was found that there was a significant increase in HDL-C, whereas, in the intervention groups, there was a significant decrease in HDL-C.

  To improve their weight and health, overweight women with PCOS should modify their lifestyle by ketogenic diet and engaging in regular exercise. However, this is limited to overweight and obese women with PCOS; more research is needed.