Determine the antibiotic resistance patterns and tsst-1 gene frequency in staphylococcus auresu strains isolated from patients of Imam Khomeini hospital in Ahvaz

isolates of Staphylococcus aureus from different samples to determine antibiotic resistance and Staphylococcus aureus is a major cause of hospital acquired infections and community. Toxic shock syndrome toxin -1 gene secreted by the bacteria from the categories are important virulence factors and is component super antigens toxins pyrogenic (PTSAgs). The purpose of this study is determine the antibiotic resistance patterns and tsst-1 gene frequency in Staphylococcus aureus strains isolated from patients of Imam Khomeini hospital in Ahvaz. In this study, 133 clinical frequency tsst-1 gene were studied. After genomic DNA extraction using DNA extraction kit was performed the definitive diagnosis of bacteria, Then the gene tsst-1 frequency done in the presence of specific primers and antibiotic resistance was determined by agar disk diffusion method. After PCR amplification and detection of the bacterium, Of 133 isolates sequence tsst-1 gene was observed in 6 strains. In antibiogram test the greatest resistance to cefazolin (3/83%) and the lowest resistance to nitrofurantoin and vancomycin (0%) was observed. Due to the increasing prevalence of resistance to antibiotics of clinical importance tsst-1 gene timely identification and implementation of appropriate therapeutic strategies for controlling infection seems necessary.