Evaluation of the relationship between left ventricular diastolic function and longitudinal myocardial strain with echocardiographic parameters in Type 2 diabetic patients

This study aimed to investigate the relationship between left ventricular diastolic function, longitudinal myocardial strain, and echocardiographic parameters in diabetic patients. This cross-sectional analytical study included all eligible type 2 diabetes patients referred to Seyed al-Shohadah Hospital, Urmia, Iran from March 2021 to February 2022. All the participants had an echocardiography examination. Demographic characteristics including age, sex, duration of diabetes, smoking, and body mass index (BMI) were recorded at the time of the echocardiography examination. This study included 140 participants, 70 were diagnosed with type 2 diabetes mellitus (T2DM) and 40 were considered healthy control group. The mean age of participants was 47.79±7.08 years for diabetics and 47.23±6.5 years for controls. A significant correlation was observed between diabetes duration and the echocardiography values of E/e', DT, MPI, and D (p < 0.05). A significant correlation was observed between DT (p=0.021), IVPT (p=0.037), TRvel (p=0.002), and a-sep values (p< 0.001) and smoking in diabetic patients, with a negative correlation. Moreover, a statistically significant positive association was established between E/e´ (p=0.043), e' (p=0.007), e-lat (p=0.046), e-sep (0.003), and a-lat (p=0.003) values and smoking in diabetic patients. Furthermore, GLS scores and diastolic dysfunction exhibited a statistically significant association with smoking and BMI variables. This study demonstrated a statistically significant association between diastolic dysfunction and global longitudinal strain (GLS) in both diabetic and control groups. This suggests that GLS can be utilized to assess the severity of diastolic dysfunction in diabetic patients during the early stages of heart failure.