Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes

This study aimed to investigate the effects of short-term supplementation with coenzyme Q10 (CoQ10) on markers of oxidative stress and inflammation, specifically superoxide dismutase (SOD), malondialdehyde (MDA), and interleukin-6 (IL-6), following exhaustive aerobic exercise in judo athletes.

Sixteen male judo athletes participated in a randomized, double-blind, crossover study in which they received CoQ10 or placebo. Participants received CoQ10 supplementation for 30 days after completing a first bout of exhaustive aerobic exercise, then completed a second bout of exhaustive exercise. Blood samples were collected before exercise, immediately, and 24 hours after exercise during the two bouts to measure levels of SOD, MDA, and IL-6. These markers were analyzed using enzyme-linked immunosorbent assay (ELISA) and spectrophotometric techniques.

CoQ10 supplementation significantly increased SOD levels after 30 days of supplementation compared to the placebo group (p<0.05). MDA and IL-6 levels were significantly reduced during the recovery period after CoQ10 supplementation (p<0.05). These findings suggest that CoQ10 effectively enhances antioxidant defences and reduces lipid peroxidation and inflammation induced by exhaustive aerobic exercise.

CoQ10 supplementation improves oxidative stress and inflammatory responses in judo athletes after exhaustive aerobic exercise. CoQ10 may be an effective nutritional strategy to enhance recovery and reduce exercise-induced cellular damage in high-intensity sports