Micelle promoted synthesis of schiff base ligands derived from 4-methyl-1,2,3-thiadiazoles-5-carboxylic acid hydrazide in bio based green media

The formation of Schiff bases are usually carried out using an acid or base catalyst in organic solvent, use Dean-Stark apparatus and dehydrating agents for removal of azotropic water. This article describes an efficient and eco-friendly synthesis of schiff base ligands, has been developed by the reaction of various benzaldehyde (1) with 4-methyl-1,2,3-thiadiazoles-5-carboxylic acid hydrazide (2) using SDS surfactant in aqueous bio based reaction medium, ethyl lactate: water. This method has more advantage as compare exiting methods such as clean reaction conditions, shorter reaction time, high yields, bio based, inexpensive and nonhazardous reaction medium with non-tedious workup. Herein synthesized compounds were characterized by various techniques such as FT-IR, 1HNMR, 13CNMR. Mass spectra and CHNS analyses.