Neuropsychological function and its relationship with psychosocial function and clinical features in Bipolar Disorders

The main aim of present study was the neuropsychological functioning across different states of bipolar illness. Several domains of cognitive functioning were examined in 15 depressed bipolar patients$ 15 manic bipolar patients$ and 15 euthymic bipolar patients. The comparison group consisted of 15 healthy subjects without history of neurological or psychiatric disorders. Neuropsychological battery assessed executive function$ attention$ and verbal and visual memory. ANOVA and Pearson correlation was used to analyze the data.No significant differences were found between depressed$ manic$ and euthymic bipolar groups the three patient groups showed cognitive dysfunction in verbal memory and executive function in relation to the comparison group. A poorer performance was observed in all bipolar groups regarding executive function and verbal memory in relation to the healthy comparison subjects.