Lanthanides (III) Polychelates with Benzophenone-based Resin Derivatives and Study of their Antimicrobial Activities

The polymeric ligand (resin) was prepared from 2-hydroxy-4-methoxybenzophenonewith 1,3-butane diol in presence of polyphosphoric acid as a catalyst at160°C for 13 h. The poly[(2-hydroxy-4-methoxybenzophenone) 1,3-butylene]H(HMBP-1,3-BD) forms, 1:2 metal:ligand chelates with La(III), Pr(III), Nd(III), Sm(III),Gd(III), Tb(III), and Dy(III). The polymeric ligand and its polychelates were characterizedon the basis of elemental analyses, electronic spectra, magnetic susceptibilities,thermogravimetric analysis, and NMR and IR spectroscopies results. The molecularweight was determined using number average molecular weight (n) by the vapourpressure osmometry (VPO) method. All the polychelates are paramagnetic in nature.The resin and their polychelates were tested for antimicrobial activity against E. coli,B. substilis, and S. aureus (bacteria) and S. cerevisiae (yeast). It is found that the synthesized polychelates can be used as antibacterial agents.