Columnar Cell Carcinoma of the Thyroid: A Case Report

The present case report concerns a 42-year-old female who referred with an enlargement of right lobe of thyroid gland since 6 months ago. Subtotal thyroidectomy specimen grossly revealed white-colored and poorly-demarcated nodule with papillary growth pattern. Microscopic examination mostly exhibited papillae lined by tall columnar cells containing pseudostratified nuclei which resembled those of follicular carcinoma and was significantly different from conventional (ground glass) appearance of papillary carcinoma. Ultimately, histopathologic diagnosis was rare columnar cell carcinoma of the thyroid gland.