Standard Full Field Electroretinography: Normal Values and Variations with Age in an Iranian Population

To determine normal values of standard full field electroretinography (ERG) and to evaluate variation with age in an Iranian population. The amplitudes and implicit times of ERGs from 170 normal subjects aged 1 to 80 years were recorded according to the International Society for Clinical Electrophysiology of Vision. Study participants included subjects who refered to our clinic for spectacle or other patients attendants and personnel of the hospital. Light-adapted ERG including single-white flash, 30-Hz flicker as well as dark-adapted ERG including rod, maximal dark-adapted and cone responses were compiled. There were no significant differences between men and women, or between right and left eye in terms of amplitude or implicit times of ERG. An increase in amplitude and implicit time was observed in 70-80 year-old subjects as compared to younger individuals (P=0.04 and P=0.03, respectively). ERG records are significantly diminished with advanced age. Our results are a suitable reference for evaluation of standard ERG responses.