COST EFFECTIVENESS OF LIVESTOCK VACCINATION FOR BRUCELLOSIS IN WEST-AZERBAYJAN PROVINCE

Brucellosis is a widespread, economically devastating and highly infectious zoonosis. Mass immunization has become a favorite strategy to control of disease. in, this study, we tried to estimate marginal effectiveness of livestock immunization program in West-Azerbayjan province. Epidemiological data about of brucellosis was gathered through literature review, expert opinion, existing resources of data and synthesis by modeling of other data and transmission of disease pattern. In a state transition model different stages of disease and intervention in three scenario (cover of immunization with 50%, 80% and 0%)were simulated and estimate the economic benefit and cost –effectiveness through the control of brucellosis by mass vaccination of livestock. In a scenario of cover with 50% reduction of brucellosis transmission between animals achieved to vaccination, estimated intervention costs were 102270000000R(Iranian Rials) & the overall disease cost reduction due intervention was 269124000000 R (Iranian Rials) and benefit-cost ratio is 322%. In a scenario of cover with 80%, estimated intervention costs were 163710000000R (Iranian Rials) & the overall disease cost reduction due intervention was 322125000000 R (Iranian Rials). Our study showed that effectiveness of immunization against brucellosis is quite significant. Calculation using basic estimates of cost of intervention program implies that this intervention is possibly very cost-effective and if with other interventions, such as control and limitation of livestock mobility, the eradication of disease is available aims.