Hepatitis A Virus and Coronary Artery Diseases

Many studies have reported on the association between human coronary artery disease (CAD) and certain persistent bacterial and viral infections. The aim of the present analysis was to investigate the possible association between HAV infection and angiography proven CAD. Blood from 200 patients undergoing coronary angiography was tested for antibodies to HAV by enzyme immunosorbent assay at Madani Heart Hospital, Tabriz University of Medical Sciences, Iran. CAD prevalence was 90% in HAV seropositive and 84.4% in HAV seronegative patients (Pv= 0.2). This analysis demonstrated that HAV seropositivity is not a risk factor for CAD.