Assessment of PD-1 gene variation in patients with multiple sclerosis

Author(s):

Ashraf Ahmadi Shadmehri , Mohammad Hosein Nicknam M.D. , Mohammad Ali Shokrgozar mehdi Mahmoudi Student. , Shila Sarial Student. , Azam Ahmadi Shadmehri , Batool Moradi , Elham Farhadi Student. , Ali Akbar Amirzargar

Message:
Abstract:
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with presumed autoimmune origin. T cells are considered to play a pivotal role in orchestrating the self-reactive immune responses in multiple sclerosis (MS). This study was performed to investigate the role of polymorphisms of the programmed cell death 1 (PD-1) gene on susceptibility to ankylosing spondylitis. This gene codes an immunoreceptor named
Language:
Persian
Published:
Tehran University Medical Journal, Volume:68 Issue: 2, 2010
Page:
87
https://magiran.com/p758135