Assessment the relationship between anal stenosis and neonatal colic

Due to abundance of neonatal colic in neonates, there is a need to discover the etiology of this problem by performing etiologic studies. There are some reports that show the anal stenosis has a probable etiologic role in these colics. This study aimed to determine the relationship between neonatal colic and anal stenosis in the neonates presenting to Mofid children hospital during the spring to autumn of 2009 to determine. This is a case-control study. The case group was the neonates at the age of 3 months or less with a documented diagnosis of neonatal colic. The control group was age and sex matched group of neonates with case group, without any neonatal colic. A total of 192 cases were studied and there were 96 cases in each group. Diagnosis of neonatal colic was confirmed by Wessel criteria and that of anal stenosis by bougie. The data were analyzed using Chi-square test, and OR was calculated. With respect to age and sex, the cases in two groups were matched. In case group, 23 patients (24%), and in control group 1 patient (1%) had anal stenosis (OR=23; p<0.000). ‍ It appears that neonatal colic and anal stenosis have statistical relationship. Therefore, we recommend clinical trial to assess the etiologic relationship between neonatal colic and anal stenosis.