Evaluation the rate of Helicobacter hepaticus in Mus musculus in Esfahan province by PCR

Various Helicobacter species causes contamination of birds, human and other mammals. H.hepaticus infection associated with intestinal, biliary and hepatic disorders such as liver, gall bladder and pancreas cancers. Mus musculus is the most common host of this bacteria that play an important role in transmission of zoonotic infection. The aim of this study was determination of the rate of H.hepaticus in Mus musculuses of Esfahan province by PCR. This was a cross-sectional study, which was done on 261 Mus musculuses isolated in Esfahan in 2009. Following the description of mice in steril condition hepatic samples isolated. Then for identification Helicobacter genus and H.hepaticus, general and specific primers were used respectively. Helicobacter genus identified in 72% of tatal samples. Out of all Helicobacter genus 42% was be H.hepaticus. According high rate of Helicobacter species infection, it sounds that the widespread surveillance of Mus musculuses in studied area was be necessary.