The Effect of Topical Diclofenac Sodium 0.1% on the Corneal Epithelial Healing after Photorefractive Keratectomy

Author(s):

Dr. Mohammad Nasser Hashemian , Dr. Firoozeh Rahimi , Dr. Fatemeh Alipour , Dr. Ali Asghar Ahmadraji , Dr. Hamid Reza Torabi , Dr. Niloofar Tavakoli , Dr. Reza Soltani Moghadam

Message:
Abstract:
Purpose
To evaluate the effect of topical diclofenac sodium 0.1% on the corneal epithelial healing after photorefractive keratectomy (PRK)
Methods
In this prospective randomized double blind clinical trial, PRK was performed on 82 patients. Thirty-three cases of them receiving topical diclofenac four times per day after surgical procedure and 45 patients did not receive this medication as a control group. Patients were compared for corneal epithelial healing after treatment.
Results
Statistically significant delayed epithelial healing has been found in the treatment group 24 hours after PRK but corneal reepithelialization has been completed in all patients four days after surgery.
Conclusion
Postoperative topical diclofenac used following PRK may delay the epithelial healing.
Language:
English
Published:
Journal of Current Ophthalmology, Volume:23 Issue: 2, Jun 2011
Page:
27
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