The aim of this study was to identify the factors affecting individual development in knowledge-based companies. The research method used was exploratory. The research population included human resources of selected knowledge-based companies of Pardis Technology Park and 980 network deputies of Telecommunication Company, of whom 276 were selected using Cochran's formula. In order to collect the data in the qualitative phase, a semi-structured interview was used while the quantitative phase involved a researcher-made questionnaire on the factors affecting individual development with a reliability of α = 0.92. The results of the qualitative phase led to the identification of four general factors affecting individual development, including individual factors, organizational factors, management factors, and environmental factors. By examining the ratios of the chi-square to the degree of freedom x2 / df), the goodness of fit index (GFI), the incremental fitness index (IFI), the root mean square error of approximation (RMSEA), the normalized fitness index (NFI) and the adaptive goodness of fit index (AGFI), structural equation modeling showed that the model of factors influencing individual development has a relatively good fit with the data; therefore, the identified factors in this model were confirmed.

Berardinelli-Seip congenital lipodystrophy (BSCL) is a rare genetic disorder which is usually diagnosed at birth or soon thereafter, with lipoatrophy affecting the face, trunk and the limbs. Because of the absence of functional adipocytes, lipid is stored in other tissues, including muscles and liver. Affecting individuals develop insulin resistance and about 35% of individuals develop diabetes mellitus. Hepatomegaly secondary to hepatic steatosis occurs in virtually all individuals. Hypertrophic cardiomyopathy is reported in 20-25% of affected individuals and is a significant cause of mortality. We are reporting a 2.5 year old girl with mild mental retardation, tall stature, hirsutism, lipodystrophy, and hepatomegaly. We believe that our patient suffer from Berardinelli-Seip congenital lipodystrophy.

This study was conducted to identify the factors affecting individual performance in public and private organizations to provide a conceptual model for these factors in public and private banks in Rasht. For this purpose, first, using systematic review and selection of 96 articles, with the help of qualitative content analysis method, 86 components were identified in the form of three factors: individual, organizational and extra-organizational. Then, by selecting 16 experts by purposeful sampling and snowball sampling method, which were 8 university professors and 8 bank managers, 71 components were finalized with the help of Delphi technique, and thus the conceptual model of research was validated and formed . The result showed that the elements of the model of factors affecting individual performance in public and private organizations consist of four main factors, namely individual, organizational and extra-organizational factors as influential factors and individual performance as influential factors. Although the elements of the research model are unique and specific to the banking industry in terms of implementation and implementation, but conceptually comparable to the findings and results of previous research and this is an important turning point of the present study.

Farber lipogranulomatosis is a rare inherited condition involving the breakdown and use of fats in the body (lipid metabolism). Characteristics are early-onset subcutaneous nodules, painful and progressively deformed joints, and hoarseness by laryngeal involvement In affected individuals, lipids accumulate abnormally in cells and tissues throughout the body, particularly around the joints. Three classic signs occur in Farber lipogranulomatosis: a hoarse voice or a weak cry, small lumps of fat under the skin and in other tissues (lipogranulomas), and swollen and painful joints. Affected individuals may also have difficulty breathing, an enlarged liver and spleen (hepatosplenomegaly), and developmental delay.
Here we report 6 patients with the diagnosis of farberlipogranulomatosis in the past 7 years, confirmed by mutation analysis, and detected 4 novel mutations in them. Clinical pictures in our patient were mostly,joint swelling and tenderness, and weak cry, 5 of the patients were female and only one affected boy who died at Newborn period. Three of them showed hepatosplenomegaly. Three of the patients are alive. We analysed ASAH1 gene and detected 4 novel mutations on them.

Heterotaxy syndrome with polysplenia is a congenital abnormality with malposition of the visceral organs and multiple associated abnormalities. The majority of affected individuals die during childhood due to severe cardiovascular anomalies. However, affected individuals who reach adulthood are usually asymptomatic. Anomalies of the abdominal venous system, including interruption of the inferior vena cava with azygos or hemiazygos continuation, congenital absence of the portal vein with a portosystemic shunt, preduodenal portal vein, and abnormalities of renal veins are frequent findings. Heterotaxy syndrome usually has no clinical significance except in the setting of planned vascular intervention or surgery. We are reporting an extremely rare case of heterotaxy syndrome (polysplenia) that presented with massive variceal hemorrhage due to associated venous malformation and systemic to portal venous system collaterals.

Cognitive impairment is one of the most common symptoms of multiple sclerosis. The purpose of this study was to compare the information processing speed in patients with MS and non-affected individuals. 38 patients with MS(Twenty-25 patients with Relapsing- Remitting of MS and 13 patients with Progressive- Relapsing MS). And 38 non-affected individuals with the Stroop test performed with the patient group. For data analysis, independ t-test was used. The results of this study showed that patients with MS had a weaker performance in the Stroop test than in the healthy group. In other words, patients spent more time to take the test and showed more error. Also, the group of MS patients with Relapsing- Remitting had a weaker performance in the Stroop test than those with Progressive- Relapsing MS. Regarding the damage to cognitive domains of patients with MS And its significant impact on their quality of life, Examine and accurate identification of cognitive rehabilitation programs should be one of the priorities of experts.

Bardet-Biedl syndrome (BBS) is one of the rare autosomal recessive disorders that affect multiple organs of the body. The signs and symptoms of this condition vary among affected individuals, even among members of the same family. We present a case of BBS with features of hypogonadism and features such as marked central obesity, retinitis pigmentosa, polydactyly, renal abnormalities and mental retardation, along with a brief review of the literature. The patient had end stage renal disease and managed with dialysis. This case also exemplifies the need for multidisciplinary approach in the management of such cases.

Trust and risk are the most important factors affecting individual behavior in the social networking platform. Individual behaviors on social media are divided into three general types: acceptance behavior, sharing behavior, and buying behavior. The Impact of Trust and Risk on Individual Behaviors There are many complexities and complexities in social networking platforms. We need a dynamic model to understand how each of the variables affect trust and risk on individual behaviors. In this article, first, using the results of previous research and surveys, trust and risk were identified as the most important factors affecting individual behaviors in social networks. In the next step, using the system dynamics approach, causal diagrams between effective variables were modeled. The relationship between the identified variables was extracted according to the paired comparison questionnaire and previous research. Dynamic model of the effect of trust and risk on individual behaviors in social networks, in three subsystems: the effect of trust and risk on individual behaviors with emphasis on employee behavior, the effect of trust and risk on individual behaviors with emphasis on user interaction, and the effect of trust and risk on individual behaviors It was designed with emphasis on the skills and competencies of the providers.

Incontinentia Pigmenti (IP) is a rare X-linked dominant disorder with skin, eye, central nervous system (CNS) and tooth abnormalities. According to the reported cases, it is estimated that there have been nearly 900-1200 affected individuals. In this article, the literature is reviewed and a case of IP with characteristic skin lesions and optic atrophy is presented.

Parkinson disease (PD) is a neurodegenerative disease of the central nervous system (CNS) with the highest prevalence in adults over 60 years of age On the other hand multiple sclerosis (MS), which mostly affects individuals between 20 and 40 years of age, is another neurodegenerative and autoimmune disease of the CNS, however, less common than PD. Here we aim to report the case of a 39‑year‑old woman, who developed PD 18 years after diagnosis of MS.