The main objective of this research was to determine the effects of soy isoflavones on serum lipids, lipoproteins and fasting blood sugar levels in hypercholesterolemic rabbits. Twenty four male New Zealand rabbits received basic pellete diet for two weeks and then were placed on hypercholesterolemic diets(pelletes plus 1% cholesterol) for three weeks. After elevation of total and LDL-cholesterol (about ten folds), groups 1-3 received 100g soy protein containing 200gr (ISO++), 100mg (ISO+) and soy protein diet without isoflavones (ISO-), for six weeks, respectively, and group 4 kept on hypercholesterolemic diet (CHO).Results showed no change in total and LDL-cholesterol levels with ISO++ diet, but two folds increases with ISO+ and ISO- in comparison with baseline and CHO diets (P<0.000). HDL-cholesterol significantly increased after ingestion of CHO diet and remained elevated (almost three folds) by the soy diets. Triglycerides and VLDL-cholesterol increased by all soy diets but only in ISO+ and ISO- diets were significantly higher than baseline (P<0.05).Fasting blood sugar levels were not changed by the soy diets. These results suggest that soy isoflavones have ameliorated the lipid profile but have not changed blood sugar levels so can exert clinical improvement in hyperlipidemias specially when cholesterol intake is simultaneously decreases.

Objective(s)Several studies have reported improved response of exercised hearts to myocardial infarction (MI). This study was aimed to evaluate the preventive role of treadmill exercise and diosgenin on cardiac marker enzymes, thiobarbituric acid reactive substances (TBARS), total antioxidant status (TAS), lipids, and electrocardiographic (ECG) patterns in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats. Materials and MethodsOne hundred Wistar rats were divided into ten groups: Control rats (C), saline (S), L-cremephor (LC), exercise (E), diosgenin dissolved in L-cremephor (15 mg/kg/day) (D), exercise+ diosgenin (E+D), ISO injected (150 mg/kg) (ISO), exercise + ISO (E+ISO), diosgenin + ISO (D+ISO) and exercise+ diosgenin+ ISO (E+D+ISO). At the end of the experiment all animals anesthetized and blood samples were collected for biochemical estimation and also the ECG patterns were recorded. ResultsExercise and diosgenin pretreatment significantly decreased the lactate dehydrogenase (LDH) and TBARS level in ISO injected animals. Exercise and diosgenin pretreatment significantly decreased serum total cholesterol and increased high density lipoprotein (HDL-C). ISO-treated rats showed pathological Q waves along with elevated ST segments. The altered electrocardiograms (ECG) of ISO-treated rats were also restored to near normal by diosgenin and exercise, but exercise and diosgenin had synergistic effects. Conclusion The present investigation demonstrates that combination of diosgenin and exercise exhibited significant protection against ISO induced electrocardiographical and biochemical changes. The cadioprotective mechanism(s) appear to be through changing lipid metabolism.

The purpose of this research is to compare organization learning in the sport clubs of Isfahan based on ISO 9000. The research method is field-descriptive survey. The research population includes all employees of four Isfahan Sports Clubs - Sepahan، Zob Ahan (having ISO 9000 standard license) and Foolad Mahan، Giti Pasand (not having ISO 9000 standard license) - and the total number. Statistical sample included 159 people. Results showed that there is a significant difference between organizational learning in sports clubs with ISO 9000 and those without ISO 9000. Organizational learning in a sports club with ISO 9000 is more than sports clubs without it. The results indicate that the sport clubs with ISO 9000 pay more attention to issues of learning and supporting new and innovative thinking.

Myocardial infarction (MI) is one of the main causes of mortality and morbidity in the world. This study was aimed to evaluate the preventive role of treadmill exercise and Diosgenin on cardiac marker enzymes, lipids and lipoproteins in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats. One hundred Wistar rats were divided into ten groups: control rats (C), saline (S), L-Cremephor alone (LC), Diosgenin dissolved in L-Cremephor (15 mg/kg/day) (D), Exercise (E), Exercise + Diosgenin (E+D), ISO injected (150 mg/kg) (ISO), Diosgenin + ISO (D+ISO), Exercise + ISO (E+ISO, and Exercise + Diosgenin + ISO (E+D+ISO). After eight weeks all animals anesthetized and blood samples were collected for biochemical estimation. Exercise and Diosgenin pretreatment decreased significantly the LDH level in ISO injected animals but only exercise can lower CK-MB level. Exercise and Diosgenin pretreatment significantly decreased serum total cholesterol and increased HDL-C. Body weight increased (p<0.05) in E group, but Diosgenin treatment lowered it in all exercise groups. Our findings confirmed the efficacy of exercise and Diosgenin pretreatment on alleviating ISO-induced cardiac damage. This effect may be resulted from positive change of lipid metabolism.

The UK office for National Statistics (ONS) is responsible for producing a wide range of inflation measures. These include the Retail Prices Index (RPI) and the UK Harmonised Index of Consumer Prices (HICP) which is used for comparisons across the European: union:One of the key components of national statistics is a public commitment to the regular quality assurance of outputs to ensure the professional quality of output. In this context ISO 9000 has become an integral part of ongoing programme designed to improve and maintain the quality of the RPI and HICP. It is now a key element underlying a formal quality management system ISO 9000.The article reviews the meaning of quality in the context of statistical outputs, the different approaches available to quality management and the potential these have to improve performance and how the latter can be measured. It describes some of the benefits that have accrued form using a formal system of quality management and takes a critical look at the lessons learnt.ISO 9000 has been to refer to the series of International Standards Organisation (ISO) Standards, expect references to specific standards such as ISO 9002 or ISO 9001 (2000) apply.

The cardiotoxic effects of isoproterenol (ISO) are associated with, and possibly due to, lipid peroxidation in heart tissue. In this study, the effect of exercise against lipid peroxidation and injuries due to isoproterenol was investigated in rat heart. 50 Wistar rats were divided into 5 groups: control rats (C), saline (S), Exercise (E), ISO injected (150 mg/kg) (ISO), Exercise + ISO (E+ISO), at the end of the experiment all animals anesthetized and heart tissue were collected for biochemical and histological examinations. Exercise increased GSH (Glutathione), GSSG (Oxidized Glutathione) and decreased TBARS (Thiobarbituric Acid Reactive Substances) levels in ISO group (p<0.05). Also, exercise reduced the rate of edema, inflammatory cells infiltration and degree of necrosis compared with control group. Our results show exercise by reduction of lipid peroxidation and intensity of myocardial injuries may have beneficial protective effects against injuries due to isoproterenol.

Deinkability of old newspaper was investigated using cellulase at different concentrations and treatment times. The results of optical properties of the made papers indicated that by increasing the enzyme concentration to 0.05 percent the brightness was increased to 47.5% ISO and yellowness decreased to 11.03% ISO. While at higher charges than 0.05 percent, brightness value the was decreased and yellowness increased. Opacity of paper was improved to 99.3% ISO by increasing the enzyme charge to 0.1% but it was reduced at higher levels than 0.1%. It was observed that enhancing of treatment time to 15 minutes and also using one-stage washing resulted in the highest brightness of 47.5% ISO, the lowest yellowness of 11.03% ISO and the opacity of 97.4% ISO. Maximum opacity was observed at treatment time of 10 minutes. With regard to the results from paper provided with enzymatic deinking of old newspaper, we could produce the papers with desirable brightness and low yellowness using optimum charge of 0.05% cellulase and treatment time of 15 minutes along with one-stage washing. We could also obtain higher opacity values using 0.1 percent enzyme or 10 minutes treatment time.

T h e iso clinism o f L i e algebra i s widely used i n the classification o f Lie algebra. This concept has a weaker structure than t h e concept o f the isomorphism. T h e iso clinism o f Lie algebra was first introduced by the Moneyhun and later it is generalized by others to n- iso clinism in Lie algebra, as well as, to the iso clinism in a pair of Lie algebra in the literature. In this paper, we study the n- isoclinism in Lie algebra and prove some of the features of the n- iso clinism in Lie algebra. For example, we prove that if L 1 and L 2 are two Lie algebras that the intersection of their centroid and F rattini algebra are zero, then, the iso clinism L 1 and L 2 are equivalent to their central factors.

Since the ISO 30401 Standard of Knowledge Management Systems is still confronted with ambiguities, its implementation by organizations, incompatibility, and doubts. The purpose of this study is to investigate whether ISO 30401 can be used as a new criterion for value -making and knowledge management research and the basis for certification? This article is an analytical -descriptive approach and content analysis that describes the structure and content of ISO 30401 and systematically uses the components and stimuli of the research identified from identified research of the knowledge management studies validating and testing them. To achieve this, databases were identified and categorized from articles containing these components and published between 2010 and 2021, and finally 57 qualitative researches out of 271 researches were chosen. The findings showed that ISO 30401 successfully combines a variety of studies in an international practical standard. This research explains how ISO 30401 standard and certification may help create value and refer to possible management initiatives to realize value increase; Provides guidelines for further operationalization by certification and implementation organizations by managers and what they should do to add value when implementing ISO 30401.