Jundishapur Journal of Health Sciences
Volume:13 Issue: 2, Apr 2021

Context: 

Numerous studies have shown the high frequency and antibiotic-resistant patterns of Shigella species in different provinces of Iran. In this study, we performed a comprehensive review from 2000 to 2020 in Iran to describe the prevalence rate and antibiotic-resistant patterns of S. sonnei, S. dysenteriae, S. flexneri, and S. boydii.

Evidence Acquisition: 

We systematically searched the biomedical databases including Scopus, Google Scholar, PubMed, SID, and Web of Science for related articles published in English or Persian. Finally, out of 70 articles, 34 studies were included in the study.

 From 44,292 clinical specimens, 2,742 cases were introduced as positive samples for Shigella species in Iran during 2000 - 2020. Also, S. sonnei (n = 1484, 54.1%) was the predominant species in Iran, followed by S. flexneri (n = 1100, 40.1%), S. dysenteriae (n = 80,3%), and S. boydii (n = 78, 2.8%). These Shigella species showed maximum resistance to ampicillin (n = 1759, 64% - 96%), cotrimoxazole (n = 1220, 87% - 100%), nalidixic acid (n = 649, 10% - 82%), trimethoprim-sulfamethoxazole (n = 459, 80% - 98.5%), cefotaxime (n = 410, 53% - 63%), and tetracycline (n = 386, 36% - 94%). No resistances were found against imipenem, meropenem, cefoxitin, norfloxacin, levofloxacin, azithromycin, and amoxicillin. Also, 308 and 359 cases were introduced as multidrug resistance (MDR) and extended spectrum beta lactamase (ESBL) producing species, respectively.

 Evaluation of endemic shigellosis and antibiotic-resistant patterns through epidemiological studies are necessary to promote infection control strategies. These data may be useful to avoid empirical treatment, revise treatment guidelines, and decrease antimicrobial resistance of Shigella spp. in human societies.

 Research on the effects of interval training on lipid profile and hematological indices is limited.

 Therefore, the purpose of this study was to determine the effects of eight weeks of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on aerobic performance, body composition, lipid profile, and hematological indices in overweight adolescents.

 Thirty overweight boys (13 - 16 years) participated in this study and were randomly divided into three groups, including the control (n = 10), HIIT (n = 10), and MICT (n = 10) groups. HIIT training (4 × 4-minute) was performed with an intensity of 95 - 85% of maximum heart rate, and MICT training (35-minute) was performed with an intensity of 70 - 60% of maximum heart rate, three sessions per week for eight weeks. Beep test and ELISA technique were used to measure aerobic performance, lipid profile, and hematological indices, respectively. The two-way repeated-measures ANOVA was used to determine the differences with a confidence interval of 95% (α = 0.05).

 The results showed that except for the variables of glucose, triglyceride (TG), and low-density lipoprotein (LDL), all other variables in the HIIT group had a significant change compared to the pre-test (P < 0.05). Also, the results showed that there was a significant difference between the HIIT and control groups in fat percentage, VO2Max, high-density lipoprotein (HDL), iron, and hemoglobin value (P < 0.05).

 The results suggest that HIIT training can be as effective as continuous strategy training to reduce the risk factors associated with cardiovascular disease in overweight adolescents.
 

 Divorce is one of the most stressful life events leading to increased susceptibility to diseases and mood disorders such as hypochondriasis.

 The present study aimed to investigate the effectiveness of acceptance and commitment therapy (ACT) on hypochondriasis and psychosocial adjustment in divorced women in Tehran.

 The research method was quasi-experimental with a pretest-posttest design and a control group. The statistical population in this study consisted of divorced women suffering from divorce-induced psychological distress who visited counseling centers in Tehran in 2018. The sample consisted of 30 divorced women selected by convenience sampling method. The participants were randomly divided into experimental and control groups (n = 15 per group), and the pretest was performed for the experimental and control groups before the intervention program. The experimental group underwent ten sessions of ACT (90-minute sessions per week), and the control group did not receive any treatment. The research instruments included the Health Anxiety Inventory (HAI) and the Psychosocial Adjustment to Illness Scale (PAIS). The Shapiro-Wilk test, Levene test, Pearson correlation coefficient, and analysis of covariance (ANCOVA) were used to analyze the data.

 The results indicated that the ACT-based intervention significantly reduced hypochondriasis in divorced women (P = 0.043). In addition, ACT improved the psychosocial adjustment in these women (P = 0.0001).

 This intervention decreased anxiety under difficult conditions and also improved psychosocial adjustment in divorced women. Therefore, ACT can be used as an effective approach in reducing social and interactional problems and also anxiety in divorced women.

 The oral mucosa is damaged in a significant percentage of patients with lupus, with the main oral lesions being ulcers, erythematous lesions, and discoid lesions. The prevalence of these lesions is estimated to vary from 9% to 45% in systemic disease and 3% to 20% in local skin disease.

 One of the symptoms of lupus is its oral manifestations. Therefore, we decided to conduct a study to investigate the prevalence of oral manifestations in lupus patients referred to Shahid Mohammadi Hospital in Bandar Abbas.

 In this descriptive cross-sectional study, the recorded information of patients with lupus referred to Shahid Mohammadi Hospital in Bandar Abbas from 2018 to 2019 was reviewed. All enrolled patients met the American College of Rheumatology criteria for classifying lupus. Recorded information, including demographic characteristics and various clinical manifestations, was recorded after examining the patients. Data were analyzed using SPSS-22 software.

 A total of 76 patients were studied. Of them, 23 (30.2%) were males, and 53 (69.8%) were females. The mean age of the participants was 6.1 ± 42.9. The most common site of oral lesion in the participants was the lip area (36 patients), followed by buccal mucosa (22 patients), hard palate (14 patients), and dorsal surface of the tongue (four patients). The majority of the clinical manifestations of the lesion were wounds (36 individuals), followed by white and red lesions (20 patients), non-cleansing white lesions (12 patients), and red lesions (eight individuals).

 Oral symptoms are usually the first signs of this disease. For this reason, dentists have an important role to play in diagnosing emerging autoimmune diseases. Ulcers are the most prevalent clinical manifestations, according to this study, and the lips are the most prevalent location. As a result, in patients with systemic lupus erythematosus, these two findings should be given greater importance than others.

 To succeed in the health tourism industry, a developing market that is able to annually generate over $60 billion in income, the factors playing an important role in this industry need to be strengthened and developed.

 Thus, the present study was aimed at identifying the factors affecting health tourism development in Khouzestan Province in 2019.

 This was a mixed methods study conducted in 2019 in two stages. The first stage aimed to identify and categorize the factors affecting health tourism development by reviewing the articles in the health tourism field during 2000 - 2019. The second stage aimed at prioritizing the identified factors through the hierarchical analysis method. The study population included academic and executive experts in the field of health tourism in Khouzestan Province who were chosen using the purposive nonprobability sampling method. Data were analyzed using Expert Choice software and SPSS version 22.

 The first stage led to identifying six main criteria, including socio-cultural, facilities and infrastructure, policymaking and planning, effective marketing, political-legal, and economic, and 38 sub-criteria. Prioritizing the factors in the second stage also indicated that the facility and infrastructure criterion with 0.268 and the political-legal criterion with a score of 0.07 had the highest and lowest relative importance, respectively. Also, the economic criterion with 0.231, policymaking and planning with 0.176, effective marketing with 0.144, and socio-cultural criterion with a score of 0.105 were ranked second to fifth, respectively.

 In sum, improving medical and non-medical facilities and infrastructure in Khouzestan Province is of high priority. Therefore, it is emphasized to empower medical staff along with using the capacity of start-ups related to tourism development in this province.

 Down syndrome (DS) screening has been integrated into prenatal care programs in Iran.

 Using cost-benefit analysis (CBA) method, this study aimed to evaluate the economic aspects of combined first trimester screening in Iran.

 The population of this descriptive cross-sectional study included all pregnant women in Tehran, Iran. A decision tree model was used to determine the costs and benefits of diagnosing and averting a DS fetus through screening. Direct and indirect costs of diagnosis and the incremental living costs of DS children in 2019 were calculated from societal perspective and compared with each other.

 The cost of identifying a fetus with DS in Iran is approximately equal to 611 million Tomans (about 25,000 USD), and the incremental living cost of DS children (benefits) was about 34 million Tomans (about 2,270 USD). The net monetary benefit was negative due to the lower incremental living cost of a DS child than the cost of finding the affected fetus.

 The result of this study showed the screening tests for DS needs revision and consideration in Iran, and due to the high cost of screening, coverage with insurance organization is necessary.

 Dioxins and dioxin-like chemicals composed of 419 compounds are a large group of compounds, including polychlorinated di-benzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and biphenyls (PCBs). Dioxins are extremely persistent in the environment and disperse in a great distance from the emission source, and bioaccumulation in the food chain is one of their critical properties. The incidence of breast cancer among Iranian women is about 30 to 35 per 100,000 cases. The present study is a systematic review of published studies in English language to discover the relationship between exposure to dioxin compounds and breast cancer.

We conducted a comprehensive literature review utilizing PubMed, Embase, Scopus, and ISI web of science databases. The MeSH-based keywords used included Organic Chemical (MeSH) OR Dioxins (MeSH) AND cancer (MeSH) OR Breast cancer (MeSH) AND Breast disease (MeSH).

The review of the literature indicated a significant positive association between dioxins exposure and the risk of breast cancer. Only in one study, breast cancer mortality rate was reported in terms of exposure to dioxins, and standardized mortality rates (SMRs) were determined.

Although there were limitations in this study, statistical analyses in various epidemiological studies demonstrated that dioxins exposure is linked to an increased risk of breast cancer.