فهرست مطالب

Thrita
Volume:11 Issue: 30, Dec 2022

  • تاریخ انتشار: 1402/01/16
  • تعداد عناوین: 6
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  • Mana Jameie, Nastaran Keshavarz Mohammadi *, Hossein Hatami, Melika Jamie, Pejman Mansouri Page 1
    Background

     The mental health status of medical students is not optimistic. Understanding the factors associated with their poor mental health can contribute to alleviating this condition.

    Objectives

     This study aimed to examine the mental health status of medical interns and its associated demographic and personal traits.

    Methods

     From 2020 to 2021, 358 interns were enrolled in the study. Goldberg's general health questionnaire (GHQ-28) was used to assess their mental health, with scores ≥ 24 indicating poor mental health. Factors associated with GHQ scores were determined using multivariable regression.

    Results

     Among the study population (age: 25.43 ± 2.31, 49.4% males), GHQ mean score was 30.09 ± 14.44, and 61.7% of interns had GHQ ≥ 24. Female gender (adjusted-OR: 1.78, P: 0.015), low hope for career prospects (adjusted-OR: 4.09, P: 0.001), and low and medium personal life satisfaction (adjusted-OR: 10.94, P < 0.001; adjusted-OR: 2.55, P: 0.001, respectively) significantly increased the risk of having poor mental health.

    Conclusions

     In Iran, more than half of medical interns are not enjoying desirable mental health. Female students are more prone to being mentally unhealthy. Furthermore, lower hope and personal life satisfaction levels negatively affect students' mental health. Related university officials should identify the causes and develop effective preventive and therapeutic mental health services for interns. Female students should be the priority group.

    Keywords: Health Promotion, Students, Medical, Mental Health
  • Roghayeh Roshani, Fatemeh Ashrafi *, Elham Moslemi, HamidReza Khaledi Page 2
    Background

     In recent years, many studies have focused on the dysregulation of miRNA expression in cancer. These structures act as oncogenes and suppressors. In the present study, the expression levels of miR-3173-3p and miR-4772-3p were investigated in the tissue of glioblastoma multiforme (GBM) patients and healthy individuals.

    Methods

     The present study was performed on 50 patients with GBM and 50 healthy individuals as the control group. Real-time PCR technique was used to determine the tissue levels of miR-3173-3p and miR-4772-3p. The biomarker evaluation of miR-3173-3p and miR-4772-3p was assessed using ROC curve analysis.

    Results

     The expression level of miR-4772-3p was higher in women with GBM (P-value = 0.03). Increased concentration of miR-3173-3p in tissue of GBM patients showed a significant correlation with a final grade of disease progression (grades III and IV) (P-value = 0.007). ROC curve analysis and cut-off of 0.6939 showed that miR-4772-3p could detect the presence of malignant GBM with 88.89 sensitivity and 100.0 specificity.

    Conclusions

     The present study reveals the potential oncogenic role of miR-4772-3p. Moreover, the progression of glioblastoma cancer in the final stages can be assessed by measuring the level of miR-4772-3p in patients’ tissue.

    Keywords: miR-3173, miR-4772, Glioblastoma Multiforme, Real-time PCR
  • Seyed Amirhossein Emamian Shirazi, Alireza Hashemi Oskouei *, Parisa Hejazi Dinan Page 3
    Background

     Vertical jump performance depends on the take-off velocity of the body's center of mass. This velocity results from vertical acceleration provided by applied force to the ground from the feet. Therefore, forces generated in the muscles and the way these forces transfer to the feet affect vertical jump performance.

    Objectives

     This study aimed to assess the correlation of vertical jump height with ground reaction force and anthropometric parameters of professional male athletes in volleyball, basketball, and wrestling.

    Methods

     In this study, the descriptive method (correlation assessment) was used to investigate the relationship of countermovement vertical jump height with ground reaction force and anthropometric parameters of 18 male professional athletes.

    Results

     This descriptive study indicated that the vertical jump height was significantly correlated with the maximum vertical force (Pearson correlation coefficient = 0.658), maximum rate of vertical force development (Pearson correlation coefficient = 0.399), negative impulse (Pearson correlation coefficient = 0.192), and positive impulse (Pearson correlation coefficient = 0.381). In addition, among 16 anthropometric parameters, only sitting height had a significant correlation with jump height (correlation coefficient = 0.499). However, the four dimensionless anthropometric parameters, including body fat mass to body mass ratio, skeletal muscle mass to body mass ratio, upper limb mass to body mass ratio, and lower limb mass to body mass ratio, were significantly correlated with vertical jump height.

    Conclusions

     The normalized body composition and ground reaction force parameters were significantly related to vertical jump performance. Therefore, designing a training program to enhance these parameters would improve vertical jump performance. According to this study, enhancing GRF characteristics could be considered valuable in such training programs.

    Keywords: Anthropometry, Body Composition, Ground Reaction Force, Sports, Vertical Jump
  • Mozhgan Harfsheno, Elaheh Shams *, Vahideh Abdollahi, Fatemeh Javani Jouni Page 4
    Background

     Infertility has increased in recent years. About half of all infertility cases are due to male factors.

    Objectives

     The present study aimed to diagnose infertile individuals by examining sperm volume, density, motility, count, pH, luteum hormone (LH), follicle-stimulating hormone (FSH), percentage of sperm with abnormal morphology, and percentage of sperm DNA damage.

    Methods

     This study was performed on semen samples of 96 individuals, of whom 45 were fertile and 51 were infertile. Sperm parameters were evaluated based on the World Health Organization (WHO) criteria among fertile and infertile individuals.

    Results

     Volume, concentration, and motility were significantly lower in infertile individuals than in fertile individuals, and LH, FSH, and the percentage of sperm DNA damage were higher in infertile individuals than in fertile individuals.

    Conclusions

     By examining the quality and analysis of semen in men, it is possible to identify infertile people and follow the necessary and appropriate treatment strategies.

    Keywords: Male Infertility, Semen Analysis, Sperm DNA Damage
  • Habib Omranikhoo, Sanaz Zargar Balaye Jame, Farhad Lotfi, Mehdi Rezaee *, Layla Ghorbanalizadeh, Hedayat Salari Page 5
    Background

     Outsourcing as an efficiency-oriented approach was introduced to elevate productivity in the public sector. This strategy as a public-private partnership (PPP) arrangement was coined to increase efficiency and quality in public organizations.

    Objectives

     In this study, we aimed to investigate the quantity of applying common outsourcing models at Bushehr University of Medical Sciences (BUMS).

    Methods

     This descriptive and cross-sectional study was conducted in 2020 at BUMS. The research population was all BUMS deputies, hospitals, and health networks. This study was carried out in three stages, including a literature review, the construction of a checklist and finally the quality assurance of gathered data. Descriptive indices were calculated using excel software version 2016.

    Results

     Results showed a total of seven various outsourcing models on which 189 cases of services had been outsourced. Of the 189 cases, 108 were clinical, and the rest were non-clinical. Among the outsourcing models, the service purchasing model was the most typically used, and leases and divestitures were the two least used models.

    Conclusions

     Although various outsourcing models are available, they have been disproportionately utilized, showing that to spread the domain of penetration of this strategy, we need to tackle the obstacles ahead of its successful implementation. Increasing the knowledge of managers could be an effective solution. Furthermore, capacity–building toward raising the number of private healthcare providers could facilitate the implementation of an outsourcing policy.

    Keywords: Public-private Partnership, Public-private Cooperation, Outsourcing, Quasi-market, Outsourced Services
  • Karim Javidaneh, Atousa Moradzadegan * Page 6
    Background

     The ability of anhydrobiotic to survive long periods of stress conditions is associated with high trehalose levels found in these organisms as a responsive mechanism against stress and adverse conditions. Many methods and factors function as determinant agents of trehalose production and preservation in yeasts.

    Objectives

     This study aimed to investigate the effect of three parameters on trehalose synthesis, including temperature, rate of feed, and time of aeration.

    Methods

     To induce trehalose production in baker's yeast, we used an experimental design method in an industrial fermenter at the Khuzestan Yeast Company. The investigation of temperature, rate of feed, and time of aeration parameters in our recipe design were also performed after the cessation of feeding molasses.

    Results

     The findings showed that temperature had the greatest effect on the synthesis of trehalose. Moreover, the interaction of three parameters was significantly effective for the stimulation of trehalose synthesis. We could also make a gas production surge in the dough by increasing the level of trehalose.

    Conclusions

     We conclude that controlling the temperature and taking advantage of the interaction between temperature, rate of feed, and aeration time can help achieve the most effective trehalose synthesis and ensuing gas production in the dough.

    Keywords: Trehalose, Saccharomyces cerevisiae, Stress Conditions, Temperature, Aeration Time, Rate of Feed