مجله زنان مامائی و نازائی ایران
سال هجدهم شماره 140 (هفته دوم فروردین 1394)

Epidemiologic events show the associations of vitamin D deficiency andhypertension، cardiovascular disease and some cancers. Vitamin D is diagnosed as one of the molecules in the pathogenesis of preeclampsia. This study was performed with aim to evaluate serum level of maternal 1 and 25-hydroxyvitamin D and its relationship with preeclampsia.

This case-control study was performed on 70 mothers referred to Mashhad University hospitals from 2013 to 2014. The study was conducted on two groups of normal pregnant women and women with severe preeclampsia. The blood samples were assessed for vitamin D serum level. Data analysis was performed using the SPSS software (version 16)، and student-t and Chi-square test. P < 0. 05 was considered significant.

The mean serum vitamin D in case group was 5. 5±3. 32 (range 3-23) and in control group was 8. 05±4. 81 (range 3-37). T-test showed a significant difference between two groups in terms of mean serum vitamin D (P<0. 001).

According to the findings in this group، vitamin D deficiency was found in both groups. Vitamin D deficiency in case group is so that has caused severely clear difference. It is recommended that the study be conducted with larger sample size before pregnancy، the mothers be evaluated in terms of vitamin D level and supplement be provided to the deficient patients، and severe preeclampsia will be checked.

hematological parameters are vital in diagnosis، treatment and monitoring of many disease and health conditions. But the reference values of these parameters are influenced by various factors including race، environmental and physiologic conditions. Referring to others reference intervals or indetermination the intervals for specific populations may causes the irreparable injuries and this is of specific importance in pregnant women due to the importance of mother and fetus health. This study was performed with aim to determine the reference values of complete blood counts (CBC) during third trimester of pregnancy in Dorud.

this cross-sectional study was performed on 351 pregnant women referred to Narges hospital at Dorud city in 2013. A blood sample was taken from each individual with EDTA anticoagulant. Blood cell count، hemogolubin، hematocrit and red blood cell indices were determined using a cell counter sysmex caliber. The leulocyte differential count was performed by providing the peripheral blood smear. The data analysis was performed using SPSS software (version 15)، variance analysis، and chi-square test.

Mean Hb concentration as a factor that was analyzed in many studies was 13. 02 gr/dl in this study. Also mean White Blood Cell and Platelets cell concentration were 10. 16 and 213 (p>0/05).

the changes in the measured factors are similar to other studies. But، the reference intervals were different، meaning that different areas may have different reference intervals for blood factor determination. Therefore، this study needs to be conducted in different parts of country.

Abnormally Invasive Placenta (AIP) is considered as a life-threatening problem in obstetrics. AIP is a growing problem in the recent decades due to the advanced maternal age and increased cesarean section. This study was performed with aim to introduce a rare case of hysterectomy due to placenta accreta in a primigravid woman with increased maternal age. Case report: The patient was a primigravid 36 years old woman with 26 weeks gestational age who was admitted due to premature rupture of membrane (PROM) and vaginal bleeding. Induction of labor was performed for vaginal bleeding at 26w، 4d due to corioamniuitis. Immediately after delivery، laparotomy was performed because of massive uncontrolled hemorrhage. At last، hysterectomy was done because of failure in conservative medical and surgical management for control of bleeding. As a result of placental pathology hysterectomy، accreta reported. The increasing prevalence of AIP may be the result of increasing rate of maternal age. One of the strategies to prevent this life-threatening complication is recommendation to marriage and pregnancy at younger age.